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Initially, when epithelial cellsloose the APC tumor suppressor gene, they developsmall polyps.

It may also be useful in low-risk asymptomaticindividuals with family history of premature coronaryheart disease, although current recommendations donot support its use. Since then, he is complaining of gradual loss of appetite and weakness

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Fiberoptic saturationmeasurements are commonly calibrated regularly (every 8–12 hours) by jugular venoussampling through the tip of the catheter (36). It appears to act at anearly step (possibly uncoating) as well as at alate step (viral assembly) in viral replication

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